John Elder Robison's "Look Me in the Eye"

This autobiography provides a stark -- yet humourous -- perspective on Asperger's syndrome. Some details of his childhood are grim, but he has a quirky personality that spices the book in a way that keeps it interesting. You can feel his personality (and condition) as you read the story. He both tells you and exhibits it through the prose.

I've enjoyed reading several books on Autistic Spectrum Disorder, e.g. the books by Temple Grandin and Donna Williams's book (Nobody Nowhere and Somebody Somewhere).